In statistics, standardization is the process of defining variables on the same scale so the variables can be compared.
In the context of registries, surveys, natural history studies, and clinical studies, standardized questions refers to the same questions being asked with the same wording and in the same format and the options to answer the question are also worded the same and presented in the same format. This allows data from different registries and studies to be compared and/or combined. Common data elements are identified and developed to ensure information is collected in a standardized manner.
Defining Patient Registries and Research Networks from “Engaging Patients in Information Sharing and Data Collection: The Role of Patient-Powered Registries and Research Networks” [Internet, 2013]
National Institute of Neurological Disorder and Stroke (NINDS): Classifications of Data Elements for a Particular Disease
Rare Diseases Registry Program (RaDaR):Develop the Right Questions to Ask