Therapeutic target« Back to Glossary Index
A therapeutic target is a biological molecule, biological pathway, or physiolocal response that is associated with a particular disease process and may be inhibited or activated by a therapy in a way that will change the course of the disease in a positive way. Biological molecules that may serve as a target include DNA, RNA, protein, viruses, or bacteria.
A target must have the potential to be affected by a therapy in a measurable way. Therapeutic targets are used to screen potential therapies in the discovery phase of the therapy development process.
A comprehensive map of molecular drug targets [2017 published article]
NCATS Toolkit for Patient-Focused Therapy Development: Discovery of Therapeutic Approach