Median effective dose
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The median effective dose (ED50) refers to the dose of a drug or biologic that produces a specific beneficial therapeutic response in 50% of the population that takes that dose. A dose-response curve is used to determine the median effective does. In order to be useful, the mean effective dose of a drug or biologic should be much less the median toxic dose (TD50).

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StatPearls: ED50 [Internet, 2020]
Merck Manual Professional Version: Dose-Response Relationships
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